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The total number of prescriptions rose from 91,405 between 2007 to 115,342 in 2010 for the two most common types of drugs, costing the NHS £3.6m.
It comes after the BBC reported a national rise in prescriptions, which experts said to the recession.
The figures were released under the Freedom of Information Act by Solihull Care Trust, which manages the borough’s NHS budget, to The Silhillian.
The total number of prescriptions for serotonin-norepinephrine reuptake inhibitors rose from 20,206 in 2007 to 27,406 in 2010, an increase of 36 per cent.
The cost was £594,057.80 in 2007 and £559,037.17 in 2010. The total bill was £2.4m.
The most prescribed drug was Venlafaxine, for major depressive disorders.
The total number of prescriptions for selective serotonin reuptake inhibitors rose from 71,199 in 2007 to 87,936 in 2010, a 24 per cent increase.
The cost in 2007 was £370,152.18 and £301,950.06 in 2010. The total bill was £1.2m.
The most prescribed drug was Citalopram, for major depressive disorders. See the full data here.
Dr Clare Gerada, head of the Royal College of GPs, last month told the BBC the rise was down to better awareness amongst the public and GPs spotting symptoms more.
She said: "Of course, in times of economic problems we would expect mental health problems to worsen - and GPs are seeing more people coming in with debts racking up, or who have lost their job and are cancelling their holidays.
"They feel guilty that they can't provide for their family and these things can often act as a trigger for depression."
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